Validity of Protein Structure Alignment Method Based on Backbone Torsion Angles
نویسندگان
چکیده
منابع مشابه
Validity of Protein Structure Alignment Method Based on Backbone Torsion Angles
1Laboratory of Computational Biology & Bioinformatics, Institute of Health and Environment, Graduate School of Public Health, Seoul National University, 599 Gwanangno, Gwanak-gu, Seoul 151-742, Korea 2Interdisciplinary Graduate Program in Bioinformatics, College of Natural Science, Seoul National University, 599 Gwanangno, Gwanak-gu, Seoul 151-742, Korea †These authors equally contributed to th...
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This article introduces a novel protein structure alignment method (named TALI) based on protein backbone torsion angle instead of the more traditional distance matrix. Representing protein structure by a serial backbone torsion angles (φ, ψ), protein structure have a simple mapping relationship to protein sequence. Thus, TALI can naturally incorporate sequence information and sequence analysis...
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The backbone structure of a protein is largely determined by the phi and psi torsion angles. Thus, knowing these angles, even if approximately, will be very useful for protein-structure prediction. However, in a previous work, a sequence-based, real-value prediction of psi angle could only achieve a mean absolute error of 54 degrees (83 degrees, 35 degrees, 33 degrees for coil, strand, and heli...
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ژورنال
عنوان ژورنال: Journal of Proteomics & Bioinformatics
سال: 2011
ISSN: 0974-276X
DOI: 10.4172/jpb.1000192